Challenges to replace ACT as first-line drug

First-line Glaucoma Therapy: Choices and Challenges

LEARNING OBJECTIVES Upon completion of this activity, participants will be able to: 1. Compare SLT with medical therapy as fi rst-line therapy for the management of OAG. 2. Develop appropriate treatment goals for patients with newly diagnosed OAG based on disease status and risk profi le. 3. Describe the epidemiology of myopia and the pathophysiological mechanisms by which glaucoma develops in ...

Drug treatment is superior to allografting as first-line therapy in chronic myeloid leukemia.

Early allogeneic hematopoietic stem cell transplantation (HSCT) has been proposed as primary treatment modality for patients with chronic myeloid leukemia (CML). This concept has been challenged by transplantation mortality and improved drug therapy. In a randomized study, primary HSCT and best available drug treatment (IFN based) were compared in newly diagnosed chronic phase CML patients. Ass...

Surgery for first line drug-resistant tuberculosis.

First-line antiretroviral drug discontinuations in children

INTRODUCTION There are a limited number of paediatric antiretroviral drug options. Characterising the long term safety and durability of different antiretrovirals in children is important to optimise management of HIV infected children and to determine the estimated need for alternative drugs in paediatric regimens. We describe first-line antiretroviral therapy (ART) durability and reasons for ...

efficacy and safety of topiramate as the first - line drug in the treatment of infantile spasms

objective infantile spasms (is) is one of the catastrophic epileptic syndromes of infancy.the purpose of this study was to evaluate clinical efficacy and safety oftopiramate (tpm) as the first -line drug in the treatment of infantile spasms. materials and methods in a quasi- experimental study, efficacy and safety of tpm in rteatment of fortychildren with is who were referred to pediatric neuro...